The Science of Personalization
Your biology is not average. Neither is the research behind it. Explore expert insights, educational content and the science that powers Trifecta Health across genomics, longevity, supplementation and performance.
Your biology is not average. Neither is the research behind it. Explore expert insights, educational content and the science that powers Trifecta Health across genomics, longevity, supplementation and performance.
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Most supplement companies start with a formula and put your name on it. Trifecta Health starts with your DNA and builds from there. That means every ingredient is chosen because a specific genetic pathway in your biology called for it. No guesswork. No averages. No filler.
Every compound is pharmaceutical-grade, sourced at therapeutic doses and compounded individually in a licensed facility without fillers, flow agents or unnecessary additives. Some of what’s in your formula you won’t find anywhere on a retail shelf, because these are compounds that are expensive to source, require precise dosing and only make sense when your DNA tells us your body actually needs them.
An AM blend and a PM blend, timed to how your body actually uses each compound. No two formulas are alike because no two people are alike. That’s not a marketing line. It’s how compounding works.

Every Trifecta formula is built on a core of foundational compounds:
essential nutrients your body requires to function at its best, precisely dosed.
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An ancient Ayurvedic root that modern science has confirmed reduces cortisol — your primary stress hormone. Clinical trials show it calms the stress axis while supporting thyroid function and sleep quality. Selected when your DNA indicates your neurotransmitter system is wired for heightened stress perception.
Both Plans
Precision
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An Arctic adaptogen that thrives in extreme cold — and helps your brain do the same under stress. Recognized by European regulators as a traditional adaptogen. Works through different brain pathways than ashwagandha, which is why they’re often paired together for comprehensive stress resilience.
Both Plans
Precision
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Your brain’s construction material. This compound breaks down into choline and uridine — two molecules your brain uses to build cell membranes and produce acetylcholine, the neurotransmitter of memory and learning. Clinical trials in older adults showed measurable memory improvement.
Both Plans
Precision
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The only mushroom scientifically shown to stimulate Nerve Growth Factor (NGF) — the protein that helps your brain grow new neural connections and repair existing ones. A clinical trial in mild cognitive impairment showed significant improvement over 16 weeks. Selected when your DNA flags neurotrophic support needs.
Both Plans
Precision
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Not coffee. Not caffeine. This is the whole fruit of the coffee plant — normally discarded during coffee production — that boosted brain-derived neurotrophic factor (BDNF) by 143% in clinical trials. BDNF is your brain’s fertilizer, helping neurons grow, connect, and survive.
Both Plans
Precision
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A natural serotonin building block extracted from the African plant Griffonia simplicifolia. Your body converts it directly into serotonin — the neurotransmitter of mood, calm, and sleep — and then into melatonin for restful nights. Added only when your DNA shows your serotonin transport system needs support. Important: always tell your practitioner if you take antidepressant medication.
Both Plans
Precision
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The amino acid your brain uses to make dopamine and norepinephrine — the neurotransmitters of motivation, focus, and drive. Military research showed it preserves mental performance under extreme stress. Morning-only timing supports your natural daytime alertness cycle. Added when your DNA indicates rapid dopamine clearance.
Both Plans
Precision
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Derived from the periwinkle flower, this compound opens up blood flow to your brain by relaxing cerebral blood vessels. Used clinically in Europe and Japan for decades to support brain circulation and glucose utilization. Think of it as upgrading the blood supply to your brain’s most demanding regions.
Both Plans
Precision
Just two blends. AM and PM.
Because what your body needs in the morning is not what it needs at night.
Compounded from scratch. Delivered to your door.
Your entire supplement routine, replaced with one that actually works.
No. Trifecta Health is a precision health company that produces supplements. The supplement is the output. The work is genomic sequencing, expert interpretation, personalized planning and ongoing coaching. The formula your body receives is the result of that entire system working together. Without the DNA analysis, the consultation and the custom compounding, it’s just another bottle on a shelf.
Concierge longevity clinics offer a version of what Trifecta Health offers, but at $50,000 to $150,000 a year, accessible only to a small number of people and typically requiring in-person visits, blood draws and ongoing appointments. Trifecta Health was built to make the same level of genomic precision and personalized supplementation available to anyone who is serious about their health, at a fraction of the cost, starting from home.
Consumer DNA tests look at a limited set of genetic markers, typically focused on ancestry and a narrow range of health traits. Trifecta Health uses comprehensive genomic sequencing that examines a much fuller picture of your biology, including the specific genetic pathways that govern how your body processes nutrients, responds to exercise, manages inflammation, metabolizes hormones and ages at the cellular level. It’s the difference between a partial map and the complete blueprint.
No. Everything begins at home. Your DNA collection kit arrives by mail and uses a simple saliva swab. No blood draw, no clinic visit, no appointment required to get started. Your 1:1 consultation with a Trifecta Health Coach happens virtually.
Included in the Trifecta Health (adult) membership plan:
Included in the Trifecta Health (child) membership plan:
Your genomic report identifies which health pillars your genetics have triggered. Each pillar activates a specific set of ingredients selected because a genetic pathway in your DNA calls for them. The doses are calibrated to your profile and every ingredient works alongside the others as a coordinated system. Those ingredients are split into two formulas: an AM blend and a PM blend, timed to how your body actually uses them. Your formula is compounded individually in a licensed facility. No off-the-shelf ingredients. No pre-made blends. No two formulas are alike because no two genetic profiles are alike.
Both supplement plans are built from your DNA and include comprehensive genomic sequencing.. Precision focuses on the core 8 health pillars: diet and heart health, sensitivities, specific nutrient needs, brain health, hormone health, detoxification, physical fitness and metabolic health. Prestige adds a focus on 5 advanced optimization pillars: longevity and anti-aging, beauty and skin health, gut and microbiome support, sexual health and vitality and bone and joint health. Prestige also includes two reformulation consultations versus one for Precision. For those who want everything working at the highest level, Prestige is the optimal system.
Your first month supply of custom-compounded supplements, based on your chosen tier (Precision or Prestige) is included in your Trifecta Health membership package, along with enrollment in a monthly subscription.
Beginning 30 days after your initial order, your credit card will be charged every 30 or 90 days – depending on your selected subscription cadence – for your recurring supplement order.
Your custom-compounded formula arrives at your door in AM and PM blends every 30 or 90 days depending on your subscription. A 90-day supply saves 15%. Your formula can be updated over time as your health evolves.
Your formula is a living document. As you age, as your health evolves and as your results come in, your Trifecta Health team can adjust your formula to reflect what your body needs at each stage. This is fundamentally different from any subscription supplement service where the formula never changes.
The Prestige plan includes up to two formula reformulations a year versus one for Precision.
If required, a reformulation of your custom-compounded supplements can be requested through the membership portal contact form or by emailing concierge@trifecta.health at least 10 business days before your next scheduled subscription payment date. Also, the reformation intake form must be completed at least seven business days before your next scheduled subscription payment date.
You may cancel your subscription at any time. To do so, please submit a written cancellation request through the membership portal contact form or by emailing concierge@trifecta.health at least five business days before your next scheduled payment date.
What makes the ingredients in my Trifecta Health formula different from what I can buy at a health food store?
Every ingredient in your formula is selected because your DNA called for it, dosed at a clinically meaningful level and compounded without fillers, flow agents or additives. Off-the-shelf supplements are formulated for the average person at the average dose. Your formula doesn’t start from an average. It starts from your genome. The ingredients are also professionally sourced at therapeutic grades that most retail products don’t reach.
Every ingredient in your formula is selected because your DNA called for it, dosed at a clinically meaningful level and compounded without fillers, flow agents or additives. Off-the-shelf supplements are formulated for the average person at the average dose. Your formula doesn’t start from an average. It starts from your genome. The ingredients are also professionally sourced at therapeutic grades that most retail products don’t reach.
Because what your body needs in the morning is not what it needs at night. Some compounds work best taken with food and support energy, focus and metabolism during active hours. Others absorb better on an empty stomach and support recovery, detoxification and cellular repair while you sleep. Your AM and PM blends are timed to how your body actually uses each compound. This isn’t a convenience feature. It’s how the formula works.
Possibly more than most. The people who invest most in their health are often the ones most frustrated by the gap between their effort and their results. That gap is frequently genetic. You may be doing everything right for the average person and still missing what your specific biology actually needs. Your DNA tells us where those gaps are. Your formula fills them.
TRIA is not a chatbot. It is not ChatGPT. It is not a search engine that gives everyone the same answer. TRIA is an AI health coach trained specifically on your personal DNA. It knows your biology, your weak points and what’s viable for your body. Every answer it gives is built around your actual genome, not a generalized database. That’s what makes the guidance Trifecta Health provides fundamentally more precise and more useful than anything else available.
Yes. The Trifecta Health Family plan was built specifically for households. Even children from the same parents are biologically unique and distinct. Their nutritional needs are not the same and the average children’s vitamin accounts for none of that. The Family plan includes full genomic sequencing for two adults and two children, 1:1 consultations and custom-compounded supplements for both adults, personalized health insights for each child and 24/7 TRIA coaching for the entire family.
Every Trifecta Health formula is built on a core of foundational compounds: the nutrients your body absolutely requires to function at its best, precisely dosed and free of fillers. Premium compounds are optional additions available in the Prestige program, sourced at the frontier of longevity and performance science. Which ones appear in your formula depends entirely on which of your health pillars are triggered by your genomic results.
No. Your genetic data is never sold to third parties. Check out our Privacy Policy [hyperlink] to review the full Disclosure of Personal Data.
It doesn’t exist yet.
It won’t until your DNA tells us exactly what to build.
